The place of implementation science in the translational medicine continuum.

From Knowing to Doing—From the Academy to Practice; Comment on “The Many Meanings of Evidence: Implications for the Translational Science Agenda in Healthcare”

In this commentary, the idea of closing the gap between knowing and doing through closing the gap between academics and practitioners is explored. The two communities approach to knowledge production and use, has predominated within healthcare, resulting in a separation between the worlds of research and practice, and, therefore, between its producers and users. Meaningful collaborations betwee...

Translational research: understanding the continuum from bench to bedside.

The process of translating basic scientific discoveries to clinical applications, and ultimately to public health improvements, has emerged as an important, but difficult, objective in biomedical research. The process is best described as a "translation continuum" because various resources and actions are involved in this progression of knowledge, which advances discoveries from the bench to th...

Protective Role of Hypothermia Against Heat Stress in Differentiated and Undifferentiated Human Neural Precursor Cells: A Differential Approach for the Treatment of Traumatic Brain Injury

Introduction: The present study aimed to explore protective mechanisms of hypothermia against mild cold and heat stress on highly proliferative homogeneous human Neural Precursor Cells (NPCs) derived from Subventricular Zone (SVZ) of human fetal brain.  Methods: CD133+ve enriched undifferentiated and differentiated human NPCs were exposed to heat stress at 42°C. Then, Western-blot qua...

Design, implementation and evaluation Operational Program for Improving the Quality of Basic Clinical Skills in Nursing and Emergency Medicine Students based on Kern method

Lifelong learning along the education and career continuum: metaanalysis of studies in health professions

Introduction: Lifelong learning is an integral part of healthprofessionals’ maintenance of competence. Several studies haveexamined the orientation toward lifelong learning at variousstages of the education and career continuum; however, none haslooked at changes throughout training and practice. The objectiveof the present study was to determine if there are differencesbetween groups defined b...